解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::Sexually transmitted infections and unplanned pregnancies present a great risk to the reproductive health of women. Therefore, female-controlled vaginal products directed toward disease prevention and contraception are needed urgently. In the present study, efforts were made to evaluate the contraceptive potential of ...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/j.contraception.2003.11.002
更新日期:2004-04-01 00:00:00
abstract::Presumably, Latino women engage in little family planning because of religious or cultural objections to contraception. The purpose of this study was to examine how acculturation, religion and various demographic factors were related to the family-planning behaviors of Latino women in the United States. Data were coll...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/j.contraception.2003.10.011
更新日期:2004-03-01 00:00:00
abstract:OBJECTIVE:To determine if laparoscopic sterilization using the Filshie clip causes less postoperative pain as compared to the Falope ring during the first 24 h after surgery. STUDY DESIGN:Forty subjects were enrolled. Five milliliters of 0.5% bupivicaine was injected at each of the two incision sites and 5 mL was drip...
journal_title:Contraception
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/j.contraception.2003.09.014
更新日期:2004-02-01 00:00:00
abstract:OBJECTIVE:Determine if erythromycin is an effective agent for achieving occlusion of the Fallopian tube for nonsurgical female sterilization. METHODS:Two studies of 100 healthy volunteers requesting sterilization were planned, one in Julpia Andhermanik and the other in Kolkata (Calcutta). A readily available marketed ...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/j.contraception.2003.07.005
更新日期:2004-01-01 00:00:00
abstract::Roussel Uclaf in partnership with the INSERM unit of Prof. E.E. Baulieu first discovered mifepristone (RU486) as part of a large research program on steroidal compounds with antihormone properties. Exhibiting a strong affinity to the progesterone and the glucocorticoid receptors, mifepristone exerted competitive antag...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/s0010-7824(03)00171-9
更新日期:2003-12-01 00:00:00
abstract::Menstrual induction refers to early uterine evacuation without laboratory confirmation of pregnancy in women with delayed menses. Mechanical aspiration is the method used in many countries but, as suggested by a pilot study, mifepristone followed by a prostaglandin analogue could also be effective. We launched the pre...
journal_title:Contraception
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1016/j.contraception.2003.09.009
更新日期:2003-12-01 00:00:00
abstract::This study analyzed data gathered from a survey of online information on the intrauterine device (IUD) to determine the content and quality of information available to consumers and providers, as evidenced by the presence or absence of a series of attributes measuring the accuracy and objectiveness of information prov...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/j.contraception.2003.07.001
更新日期:2003-11-01 00:00:00
abstract::This was a double-blind randomized control study to evaluate the efficacy of cervical priming by nitric oxide donor before second-trimester induced abortion. One-hundred healthy women with a singleton pregnancy between 14 and 20 weeks of gestation were randomized into either 40 mg isosorbide mononitrate or placebo, gi...
journal_title:Contraception
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0010-7824(03)00170-7
更新日期:2003-10-01 00:00:00
abstract:OBJECTIVES:To compare the pharmacokinetic parameters and safety of the progestagen, Org 30659, (17alpha)-17-hydroxy-11-methylene-19-norpregna-4,15-dien-20-yn-3-one), and ethinyl estradiol (EE) in Caucasian and Japanese women after single and multiple doses. METHODS:This was an open-label parallel design of a single do...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/s0010-7824(03)00140-9
更新日期:2003-09-01 00:00:00
abstract:BACKGROUND:This study was conducted to assess the efficacy and incidence of side effects of a regimen of repeated doses of 400 microg sublingual misoprostol for termination of pregnancy of <7 weeks gestation. METHOD:Fifty women were given 400 microg sublingual misoprostol every 3 h for three doses. Two additional dose...
journal_title:Contraception
pub_type: 临床试验,杂志文章
doi:10.1016/s0010-7824(03)00134-3
更新日期:2003-08-01 00:00:00
abstract:OBJECTIVE:To examine from the health care services payer perspective the economic consequences of contraceptives available to women in the United States. METHODS:A Markov model was constructed to compare effectiveness and costs among nine contraceptive methods (including 3-month injectable, oral contraceptives, intrau...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/s0010-7824(03)00078-7
更新日期:2003-07-01 00:00:00
abstract::The effect of aromatase inhibitors on the implantation process is not well known. This study examined the anti-implantation action in rats of a nonsteroidal aromatase inhibitor of high specific activity, fadrozole hydrochloride (Fad). Continuous subcutaneous infusion of Fad at 300 microg/day from Day 1 (the day of spe...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/s0010-7824(03)00076-3
更新日期:2003-07-01 00:00:00
abstract::In this open-label, randomized study we compared the influence of a new oral contraceptive containing 30 microg ethinylestradiol and 3 mg drospirenone (Yasmin) with a reference preparation containing 30 microg ethinylestradiol and 150 microg desogestrel (Marvelon) on variables of carbohydrate metabolism by means of or...
journal_title:Contraception
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0010-7824(02)00537-1
更新日期:2003-06-01 00:00:00
abstract::This paper presents a secondary analysis of 3419 Norplant users from 11 countries throughout Asia, Africa and Latin America. The main objective was to identify the menstrual problems associated with a high risk of early discontinuation of Norplant use. Eligible participants were divided into two groups: those who cont...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/s0010-7824(03)00040-4
更新日期:2003-05-01 00:00:00
abstract::The objective of this study was to describe the availability of early surgical and medical abortion among members of the National Abortion Federation (NAF) and to identify factors affecting the integration of early abortion services into current services. Telephone interviews were conducted with staff at 113 Planned P...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/s0010-7824(02)00512-7
更新日期:2003-04-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to provide evidence about the mechanism of action of the Yuzpe method of emergency contraception by examining effectiveness by cycle day of intercourse relative to ovulation. METHODS:Through a literature search, we identified eight studies that present the number of women treate...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/s0010-7824(02)00486-9
更新日期:2003-03-01 00:00:00
abstract::Scarce data are available on the relation between the effectiveness of intrauterine device (IUD) and the gynecologic features of a woman. A nested case-control study was conducted to determine whether the uterine position and hysterometry affect the pregnancy rate of copper IUD. Seventy-one cases (pregnant women with ...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/s0010-7824(02)00480-8
更新日期:2003-03-01 00:00:00
abstract::This double-blind randomized control study was conducted to evaluate whether a nonsteroidal anti-inflammatory drug (NSAID) could act as an effective pain control method during first trimester suction abortion, and whether co-treatment of NSAID with misoprostol will decrease the efficacy of the cervical ripening effect...
journal_title:Contraception
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0010-7824(02)00437-7
更新日期:2003-02-01 00:00:00
abstract::Surveys undertaken in the 1970s and 1980s suggested that amenorrhea was unacceptable to most women, especially in developing countries. More recent research suggests that increasing numbers of women in the developed world prefer to menstruate less often. In a questionnaire survey of 1001 women attending family-plannin...
journal_title:Contraception
pub_type: 杂志文章,多中心研究
doi:10.1016/s0010-7824(02)00474-2
更新日期:2003-01-01 00:00:00
abstract::The rheological properties of four commercially available spermicidal gels (two polyacrylic acid derivatives and two carboxymethylcellulose based) and their dilutions with a vaginal fluid simulant (pH 4.2) and a semen simulant (pH 7.7) were measured at 25 degrees C and 37 degrees C over a biologically relevant range o...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/s0010-7824(02)00430-4
更新日期:2003-01-01 00:00:00
abstract::This randomized, double-blind, placebo-controlled exploratory study examined the efficacy and safety of a low-dose oral contraceptive (Mircette), desogestrel/ethinyl estradiol [DSG/EE] and ethinyl estradiol [EE]) in relieving the symptoms of dysmenorrhea. Twenty-three clinics in the United States enrolled 77 women (ag...
journal_title:Contraception
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0010-7824(02)00414-6
更新日期:2002-12-01 00:00:00
abstract::The objective of this study was to evaluate use of a cauda epididymis extract (CEE) as an immunocontraceptive in rats. Twenty-two rats in puberty or 19 rats that gave birth once (primipara) were immunized with intraperitoneal (IP) injection of CEE. Rats in puberty received one or two injections of CEE containing 1.5 x...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/s0010-7824(02)00406-7
更新日期:2002-12-01 00:00:00
abstract::In an open, single-group, phase III clinical trial of 5 years, the clinical performance of NOVA T 380 was investigated in three centers. The device having a higher copper surface of 380 mm(2) is a modification of NOVA T. A total of 400 voluntary women were enrolled in the study. The mean age was 31.4 years (SD 5.5) wi...
journal_title:Contraception
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1016/s0010-7824(02)00385-2
更新日期:2002-11-01 00:00:00
abstract::Hsp70-2 functions as a molecular chaperone that assists other proteins in their folding, transport and assembly into complexes, and is postulated to be linked to the mechanisms that inhibit apoptosis. Here we have determined the association between Hsp70-2 gene and germ cell apoptosis induced by a high dose of testost...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/s0010-7824(02)00357-8
更新日期:2002-11-01 00:00:00
abstract::This prospective, open-label, randomized trial of healthy adult women up to 9 weeks pregnant compared mifepristone 200 mg followed 2 days later with misoprostol 400 microg orally versus misoprostol 800 microg vaginally. The study was interrupted after the oral misoprostol group experienced a higher than expected failu...
journal_title:Contraception
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1016/s0010-7824(02)00366-9
更新日期:2002-10-01 00:00:00
abstract::Conventional oral contraceptive (OC) starting instructions require waiting until menses to begin the OC. The conventional approach requires detailed patient education about when to begin and also may require the use of less effective or less acceptable interim contraceptive protection until menses. At our urban family...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/s0010-7824(02)00351-7
更新日期:2002-09-01 00:00:00
abstract::Effect of RISUG, a newly developed male contraceptive, on various amino acids of seminal plasma ejaculates was studied by proton magnetic resonance spectroscopy at 400 MHz. Levels of amino acids were compared with the seminal plasma of obstructive azoospermia and controls. Glutamic acid, glutamine, and arginine were f...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/s0010-7824(02)00343-8
更新日期:2002-09-01 00:00:00
abstract::A study was performed to evaluate the impact of knowledge of HIV infection (diagnosis) on contraception information and choices for HIV infected women. A questionnaire was given to 140 HIV infected women. Most of the studied population included young women with a low educational level. A significant increase in the kn...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/s0010-7824(02)00332-3
更新日期:2002-08-01 00:00:00
abstract::The study was conducted to profile women seeking abortions at the National University Hospital, with particular interest in the trend of teenage pregnancies with the aim of identifying risk factors for late presentation for abortions. All patients who underwent an abortion at our center from January 1, 1996 to Decembe...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/s0010-7824(02)00317-7
更新日期:2002-07-01 00:00:00
abstract::The objective of the study was to assess the efficacy of cervical preparation with misoprostol or laminaria suction abortion up to 18 weeks gestation. The study was conducted among a consecutive case series of patients presenting for dilatation and evacuation at a single center. Cervical preparation was effected by ei...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/s0010-7824(02)00306-2
更新日期:2002-06-01 00:00:00
abstract::The purpose of the study was to evaluate semen quality in young Chinese men and to establish reference values. Normal healthy young men from seven geographical areas were enrolled. The study showed that the mean sperm volume was 2.61 mL, and mean percent of sperm with forward progression was 59.89, while median of sem...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/s0010-7824(02)00281-0
更新日期:2002-05-01 00:00:00
abstract::Since peritubular smooth muscle cells (PSMCs) have been characterized, isolated and cultured in homogeneous populations, the regulation of seminiferous epithelium contractility has received increasing attention. The present article reports and discusses experimental evidence demonstrating that: (1) PSMCs express two t...
journal_title:Contraception
pub_type: 杂志文章,评审
doi:10.1016/s0010-7824(01)00319-5
更新日期:2002-04-01 00:00:00
abstract::The objective of this study was to assess the influence of oral contraceptives (OCs) on the risk of venous thromboembolism (VTE) in young women. A 5-year case-control study including all Danish hospitals was conducted. All women 15-44 years old, suffering a first ever deep venous thrombosis or a first pulmonary emboli...
journal_title:Contraception
pub_type: 临床试验,杂志文章
doi:10.1016/s0010-7824(01)00307-9
更新日期:2002-03-01 00:00:00
abstract::In Lebanon, coitus interruptus or withdrawal remains a widely practiced method of family planning. Our research sought to understand the role of men in reproductive health in Lebanon by focusing on this common practice. Our main questions were: Why is it that the practice persists when more effective modern methods of...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/s0010-7824(01)00304-3
更新日期:2002-02-01 00:00:00
abstract::This article reviews the toxicology of polymers that are used in contraceptive implants. The two main classes of synthetic, nondegradable polymers used in the delivery of female contraceptives are silicone elastomers (e.g., Silastic) and ethylene co-vinyl acetate (EVA; ELVAX). The controversies surrounding the silicon...
journal_title:Contraception
pub_type: 杂志文章,评审
doi:10.1016/s0010-7824(01)00285-2
更新日期:2002-01-01 00:00:00
abstract::Users of subdermal contraceptive implants report long duration of use, convenience, and high efficacy as liked features and bleeding irregularities, weight loss/gain, and headaches as disliked effects of these methods. Satisfied users tend to be women who do not experience side effects or women who value positive feat...
journal_title:Contraception
pub_type: 杂志文章,评审
doi:10.1016/s0010-7824(01)00281-5
更新日期:2002-01-01 00:00:00
abstract::To determine knowledge of, attitudes toward, and use of emergency contraception (EC), interviews were held with 1068 clients of 89 public sector primary healthcare facilities in two urban and two rural areas of South Africa. Only 22.8% of the clients had heard of EC. Awareness was significantly lower in the most rural...
journal_title:Contraception
pub_type: 杂志文章,多中心研究
doi:10.1016/s0010-7824(01)00272-4
更新日期:2001-12-01 00:00:00
abstract::One-hundred-thirty of 178 women who received Norplant-2 implants were followed prospectively for 4 years. Menstrual disorders were the most common reason for discontinuation. Only one patient conceived, for a failure rate of 0.6%. ...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/s0010-7824(01)00265-7
更新日期:2001-11-01 00:00:00
abstract::The evaluation of the study was of the impact of oral contraceptive (OC) use on activated protein C (APC-resistance). Eight hundred eighteen young fertile women were screened for a study designed to compare three different marketed OC preparations. The women could have used either other oral contraceptive preparations...
journal_title:Contraception
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0010-7824(01)00253-0
更新日期:2001-10-01 00:00:00
abstract::The exact role of apoptosis that occurs in human placenta during the early stage of pregnancy remains unknown because of the difficulty in obtaining the intact implantation site. In this study, we used rhesus monkey as an animal model to examine apoptosis occurring in the implantation site at various stages of early p...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/s0010-7824(01)00241-4
更新日期:2001-09-01 00:00:00